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GlycoErase™ MAN2A2 Knockout Human Ovarian Cancer Cell A2780

CAT#: GLJF-0525-JF1079

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Overview Specification Target Information Related Products
Overview
Description
MAN2A2 knockout A2780 cells, deficient in mannosidase alpha class 2A member 2 involved in N-glycan processing, enable study of N-glycan processing disruption, potentially affecting N-glycan structure, protein glycosylation, and Golgi/membrane-associated glycosylation pathways important for ovarian tumor progression.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:3~1:6
Cell Line
A2780
Primary Disease
Ovarian Epithelial Tumor
Lineage
Ovary/Fallopian Tube
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Glutamine & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
MAN2A2
Full Name
Mannosidase alpha class 2A member 2
Alternative Name
HsT19662, alpha-MIIx, MANA2X
Location
15q26.1
Gene ID
4122
Summary
Predicted alpha-mannosidase involved in N-glycan processing; potentially localized to the Golgi apparatus and membrane.
For Research Use Only.
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