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GlycoErase™ PRKAA2 Knockout HEK293 Cell Line

CAT#: GLJF-0825-JF471

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ PRKAA2 knockout HEK293 cell line is a HEK293 model lacking PRKAA2 (AMPK α2 catalytic subunit), which regulates glucose and lipid metabolism and influences myocardial energy regulation. The knockout system supports research in glucose utilization, lipid biosynthesis, and human cardiometabolic signaling pathways.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
PRKAA2
Full Name
Protein Kinase Amp-Activated Catalytic Subunit Alpha 2
Alternative Name
AMPK; AMPK2; PRKAA; AMPKa2
Location
1p32.2
Gene ID
5563
Summary
This gene encodes the alpha catalytic subunit of AMPK, a heterotrimeric enzyme regulating cellular energy status. It phosphorylates and inactivates ACC and HMGCR, key enzymes in fatty acid and cholesterol synthesis, and is important for insulin sensitivity and myocardial energy homeostasis.
For Research Use Only.
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