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GlycoFlux™ Human ALG9 Overexpression Glycoengineered Cell

CAT#: GLJF-0925-JF241

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human ALG9 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses ALG9, an ER mannosyltransferase required for lipid-linked oligosaccharide assembly. Increasing ALG9 activity improves precursor completeness (toward Man₉GlcNAc₂), enabling higher N-glycan site occupancy, CDG-II pathway interrogation, and robustness testing of ER glycosylation under stress.
Product Type
Overexpression Cell Lines
Cell Line
As requested by the client.
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
ALG9
Full Name
ALG9 alpha-1,2-mannosyltransferase
Alternative Name
DIBD1
Location
11q23.1
Gene ID
79796
Summary
Facilitates lipid-linked oligosaccharide assembly; mutations lead to CDG II (congenital disorder of glycosylation type II); multiple transcript variants (different isoforms) may influence enzyme specificity.
For Research Use Only.
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