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GlycoFlux™ Human AMY1C Overexpression Raji Cell Line

CAT#: GLJF-0925-JF923

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human AMY1C overexpression Raji cell line is a stable cell line engineered to overexpress AMY1C, another salivary α-amylase isoenzyme responsible for initiating starch and glycogen breakdown. Together with AMY1A and AMY1B, AMY1C represents part of the salivary amylase cluster. This engineered model allows comparative studies of amylase isoforms, their overlapping and distinct roles in carbohydrate metabolism, and their potential contributions to metabolic remodeling in cancer.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Lymphoblast-like, suspension growth
Passage Ratio
1:2~1:4
Cell Line
Raji
Primary Disease
Burkitt's lymphoma
Lineage
B lymphocyte (B cell)
Lineage Subtype
Mature B cell, widely used in EBV-related studies
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
FBS & RPMI
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
AMY1C
Full Name
Amylase Alpha 1C
Alternative Name
AMY1
Location
1p21.1
Gene ID
278
Summary
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland.
For Research Use Only.
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