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GlycoFlux™ Human ILKAP Overexpression HepG2 Cell Line

CAT#: GLJF-0925-JF644

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Overview Specification Target Information Related Products
Overview
Description
GlycoFlux™ human ILKAP overexpression HepG2 cell line is a stable cell line engineered to express ILKAP, a serine/threonine phosphatase of the PP2C family that interacts with integrin-linked kinase (ILK). ILKAP modulates ILK-dependent regulation of glycogen synthase kinase 3β, influencing WNT signaling activity and cell adhesion pathways. This model supports research on integrin signaling, phosphatase regulation, and cancer-associated signaling networks.
Product Type
Overexpression Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:4~1:6
Cell Line
HepG2
Primary Disease
Hepatoblastoma
Lineage
Liver
Lineage Subtype
Hepatoblastoma
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
qPCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Glutamine
Application
Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
ILKAP
Full Name
Ilk Associated Serine/Threonine Phosphatase
Alternative Name
PP2CD; PPM1O; ILKAP2; ILKAP3; PP2C-DELTA
Location
2q37.3
Gene ID
80895
Summary
This gene produces a PP2C family serine/threonine phosphatase that interacts with integrin-linked kinase (ILK) to influence ILK-dependent regulation of glycogen synthase kinase 3 beta, impacting Wnt pathway activity.
For Research Use Only.
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