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GlycoFlux™ Human PPP1CB Overexpression CHO-K1 Cell Line (CAT#: GLJF-0925-JF326)

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1 M cells/vial*2

Description GlycoFlux™ human PPP1CB overexpression CHO-K1 cell line boosts PPP1CB, the β catalytic subunit of PP1, which regulates cell division, glycogen turnover, and neuronal function. Mouse studies link this gene to learning and memory, making this model useful for neurobiology and metabolic research.
Product Type Overexpression Cell Lines
Species Hamster
Cell Morphology Epithelial, adherent
Passage Ratio 1:3~1:5
Cell Line CHO-K1
Lineage Chinese hamster ovary
Cell Viability >90%
Sterility Test The sterility test indicated an absence of microbial growth.
Identity Test STR identification
Mycoplasma Test Negative
Virus Test Negative for HIV, HBV and HCV.
Genetic Stability Testing We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation qPCR, Sanger Sequencing
Culture Medium FBS & Penicillin/Streptomycin & Proline & DMEM
Application Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size 1 M cells/vial*2
Product Format Frozen
Shipping Dry ice
Availability Status Made to order
Handling Notes Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target PPP1CB
Full Name Protein Phosphatase 1 Catalytic Subunit Beta
Alternative Name MP; PP1B; PP1c; NSLH2; PP-1B; PPP1CD; PP1beta; PPP1beta; HEL-S-80p
Location 2p23.2
Gene ID 5500
Summary The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only.
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