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Recombinant human APOH protein (NP_000033.2) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.