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| Size | Qty | Add To Basket |
|---|---|---|
| 1 mg | ||
| 2 mg | ||
| 5 mg |
| Product Overview | Recombinant Human GZMB protein (NP_004122.2) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites. |
| Source | Glycoengineered Mannose-5 Pichia pastoris |
| Species | Human |
| Tag | His-Tag, FC-Tag or other Tags as required. |
| Purity | >90% |
| Endotoxin Level | Regular batch |
| Conjugation | None |
| Target | GZMB |
| Full Name | Granzyme B |
| Gene ID | 3002 |
| Uniprot ID | P10144 |
| Accession Number | NP_004122.2 |
| Background | The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. |
| Alternate Names | C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1 |