Recombinant Human herpesvirus 2 (strain HG52) (HHV-2) Envelope glycoprotein I (21-372 aa), E. coli (CAT#: GP05-249J)

Product Overview	Recombinant Human herpesvirus 2 (strain HG52) (HHV-2) Envelope glycoprotein I (21-372 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.
Biological Activity	Measured by its binding ability in a functional ELISA.
Source	E. coli cell-free expression system
Species	Human herpesvirus 2 (strain HG52) (HHV-2)
Fragment	21-372 aa
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	gI
Full Name	Envelope glycoprotein I
Uniprot ID	P13291
Background	In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.
Alternate Names	Envelope glycoprotein I