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Recombinant Human Myelin associated glycoprotein (MAG) (20-516 aa) [His-SUMO], E. coli

CAT#: GP02-071J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human Myelin associated glycoprotein (NP_002352.1) (20-516 aa) was expressed in E. coli with a 6xHis-SUMO-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Source
E. coli
Species
Human
Fragment
20-516 aa
Sequence
GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGP
Tag
6xHis-SUMO-tag at the N-terminus
Predicted MW
70.7 kDa
Purity
>95%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
MAG
Full Name
Myelin associated glycoprotein
Gene ID
4099
Uniprot ID
P20916
Accession Number
NP_002352.1
Background
The protein is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions.
Alternate Names
GMA; S-MAG; SPG75; SIGLEC4A; SIGLEC-4A
For Research Use Only.
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