Recombinant Measles virus (strain Philadelphia-26) (MeV) Fusion glycoprotein F0 (24-550 aa), E. coli

Recombinant Measles virus (strain Philadelphia-26) (MeV) Fusion glycoprotein F0 (24-550 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.

Measured by its binding ability in a functional ELISA.

E. coli cell-free expression system

Measles virus (strain Philadelphia-26) (MeV)

24-550 aa

His-tag or Tag free

>90%, determined by SDS-PAGE.

Unconjugated

F

Fusion glycoprotein F0

Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.

F