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Recombinant Mouse Glycoprotein hormone beta-5 (GPHB5) (25-130 aa) [10xHis-tag and Myc-tag], E. coli

CAT#: GPX04-294J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Mouse Glycoprotein hormone beta-5 (25-130 aa) was expressed in E. coli with a 10xHis-tag at the N-terminus and a Myc-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
E. coli
Species
Mouse
Fragment
25-130 aa
Sequence
SSSGNLHTFVGCAVREFTFMAKKPGCRGLRITTDACWGRCETWEKPILEPPYIEAYHRVCTYNETRQVTVKLPNCAPGVDPFYTYPMAVRCDCGACSTATTECETI
Tag
10xHis-tag at the N-terminus and Myc-tag at the C-terminus
Predicted MW
19.3 kDa
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
GPHB5
Full Name
Glycoprotein hormone beta-5
Uniprot ID
Q812B2
Background
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Alternate Names
Thyrostimulin subunit beta
Gene namesi; GPHB5
For Research Use Only.
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