GlycoErase™ PPP1R9A Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF466)

Description	GlycoErase™ PPP1R9A knockout HEK293 cell line is a HEK293 model with PPP1R9A deleted. PPP1R9A (neurabin-1) is a PDZ/SAM-domain scaffold protein regulating PP1 and actin cytoskeleton reorganization, with roles in neuronal development. The knockout supports studies of human actin remodeling, synaptic-like scaffold function, and epigenetic imprinting, with applications in development, cell adhesion, and neurobiology.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	PPP1R9A
Full Name	Protein Phosphatase 1 Regulatory Subunit 9A
Alternative Name	NRB1; NRBI; Neurabin-I
Location	7q21.3
Gene ID	55607
Summary	This imprinted gene, expressed mainly from the maternal allele in embryonic muscle, encodes a PP1 regulatory subunit with PDZ and SAM domains. It controls actin cytoskeleton remodeling and has multiple isoforms.