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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human PPP1R42 overexpression HEK293 cell line stably expresses PPP1R42, a protein that interacts with γ-tubulin and PP1 to maintain centrosome integrity. This engineered system is useful for research into centrosome separation, cell cycle regulation, and phosphatase signaling. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293 |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | FBS & Penicillin/Streptomycin & Proline & DMEM |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | PPP1R42 |
| Full Name | Protein Phosphatase 1 Regulatory Subunit 42 |
| Alternative Name | dtr; TLLR; TLRR; LRRC67 |
| Location | 8q13.1 |
| Gene ID | 286187 |
| Summary | This protein interacts with gamma-tubulin and PP1, positively regulating PP1 to maintain centrosome integrity. |