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Recombinant Human immunodeficiency virus type 1 (HIV-1) group M subtype B (isolate ARV2/SF2) Envelope glycoprotein gp160 was expressed in Mammalian cell with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
Mammalian cell
Species
Human immunodeficiency virus type 1 (HIV-1) group M subtype B (isolate ARV2/SF2)
Envelope glycoprotein gp160 oligomerizes in the host endoplasmic reticulum into predominantly trimers. In a second time, gp160 transits in the host Golgi, where glycosylation is completed. The precursor is then proteolytically cleaved in the trans-Golgi and thereby activated by cellular furin or furin-like proteases to produce gp120 and gp41.