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Recombinant Human BDNF Protein, Glycoengineered Pichia pastoris

CAT#: GLJF-0722-JF23

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Human BDNF protein (NP_001137277.1) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Source
Glycoengineered Pichia pastoris
Species
Human
Tag
His-tag, FC-tag
Purity
>90%, determined by SDS-PAGE.
Endotoxin Level
Regular batch
Conjugation
None
Target Information
Target
BDNF
Full Name
Brain-derived neurotrophic factor
Gene ID
627
Uniprot ID
P23560
Accession Number
NP_001137277.1
Background
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
Alternate Names
Brain-Derived Neurotrophic Factor; Neurotrophin; Abrineurin; ANON2; BULN2
For Research Use Only.
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