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Recombinant Human CCL7 protein (NP_006264.2) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.
Alternate Names
C-C Motif Chemokine Ligand 7; Monocyte Chemoattractant Protein 3; Monocyte Chemotactic Protein 3; Chemokine (C-C Motif) Ligand 7; Small Inducible Cytokine A7 (Monocyte Chemotactic Protein 3); Small-Inducible Cytokine A7; SCYA6; SCYA7; MCP-3; MCP3; NC28; MARC; FIC