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100 μg |
Product Overview | Recombinant Human CD44 molecule (NP_000601.3) (21-220 aa) was expressed in Mammalian cell with a mFc-Avi-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. Immobilized mouse Anti-CD44 monoclonal antibody at 3 μg/mL can bind human CD44, the EC50 is 2.52 ng/mL. This product can be used in ELISA, WB, IP. |
Biological Activity | Determined by its binding ability to CD44 monoclonal antibody in a functional ELISA. Immobilized mouse Anti-CD44 monoclonal antibody at 3 μg/mL can bind human CD44, the EC50 is 2.52 ng/mL. |
Source | Mammalian cell |
Species | Human |
Fragment | 21-220 aa |
Sequence | QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP |
Tag | mFc-Avi-tag at the C-terminus |
Predicted MW | 51 kDa |
Purity | >92%, determined by SDS-PAGE. |
Endotoxin Level | <1.0 EU/μg, determined by the LAL method. |
Conjugation | Unconjugated |
Target | CD44 |
Full Name | CD44 molecule |
Gene ID | 960 |
Uniprot ID | P16070 |
Accession Number | NP_000601.3 |
Background | The protein is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. |
Alternate Names | IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III |