Recombinant Human CD44 molecule (CD44) (21-220 aa) [mFc-Avi-Tag], Mammalian cell

Recombinant Human CD44 molecule (NP_000601.3) (21-220 aa) was expressed in Mammalian cell with a mFc-Avi-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. Immobilized mouse Anti-CD44 monoclonal antibody at 3 μg/mL can bind human CD44, the EC50 is 2.52 ng/mL. This product can be used in ELISA, WB, IP.

Determined by its binding ability to CD44 monoclonal antibody in a functional ELISA. Immobilized mouse Anti-CD44 monoclonal antibody at 3 μg/mL can bind human CD44, the EC50 is 2.52 ng/mL.

Mammalian cell

Human

21-220 aa

QIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEGHVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIP

mFc-Avi-tag at the C-terminus

51 kDa

>92%, determined by SDS-PAGE.

<1.0 EU/μg, determined by the LAL method.

Unconjugated

CD44

CD44 molecule

The protein is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis.

IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III