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Recombinant Human COL4A3 protein (NP_000082.2) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3.