Recombinant Human Fibroblast activation protein alpha (FAP), Sf9 insect cells

Recombinant Human Fibroblast activation protein alpha (FAP) (NP_004451.2) was expressed in Sf9 insect cells. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.

Determined by its binding ability in a functional ELISA.

Sf9 insect cells

Human

85.5 KDa

>70%, determined by SDS-PAGE and HPLC

Unconjugated

FAP

Fibroblast activation protein alpha

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

FAPA; SIMP; DPPIV; FAPalpha; FAP; Fibroblast activation protein alpha