Recombinant Mouse Uromodulin (UMOD) protein [His-Tag], Yeast (CAT#: GP01-125J)

Product Overview	Recombinant Mouse Uromodulin (UMOD) protein (NP_033496.1) (aa25-588) was expressed in Yeast with a His-Tag. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	Yeast
Species	Mouse
Fragment	aa25-588
Tag	His-Tag
Predicted MW	64.2 KDa
Purity	>90%, determined by SDS-PAGE and HPLC
Conjugation	Unconjugated

Target	UMOD
Full Name	Uromodulin
Gene ID	22242
Uniprot ID	Q91X17
Accession Number	NP_033496.1
Background	This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by proteolytic cleavage. It is thought to regulate water and salt balance in the thick ascending limb of Henle and to protect against urinary tract infection and calcium oxalate crystal formation. In mouse deficiency of this gene is associated with increased susceptibility to bacterial infections and formation of calcium crystals in kidneys. Alternative splicing results in multiple transcript variants.
Alternate Names	THP; Ureh; Urehd; uromu; Urehd1; Urehr4; UMOD; Uromodulin