Close
0
Inquiry Basket

There is no product in the shopping cart, buy it!

Hot Products
Monosaccharide Products
Oligosaccharide Products
Polysaccharide Products
Carbohydrate-based Surfactant Products
Blood Group Antigen Products
Glycoprotein Products
Glycopeptide Products
Nucleotide Sugar Products
Glycoprotein Assay Kits
Comprehensive Glycoprotein Reagents
Glycoengineered Cell Products
Glycoengineering Viral Particle Products
Glycolipid Products

GlycoErase™ B3GLCT Knockout IST-Mes2 Cell Line

CAT#: GLJF-0425-JF1011

Datasheet Request COA
Overview Specification Target Information Related Products
Overview
Description
The B3GLCT knockout IST-Mes2 cell line lacks B3GLCT protein, beta 3-glucosyltransferase involved in O-linked glucosylation of thrombospondin type-1 repeats (TSRs). B3GLCT knockout in IST-Mes2 cells enables study of O-linked glycosylation disruption of TSRs in Pleural Mesothelioma, potentially affecting TSR-containing protein functions, cell adhesion, signaling and thrombospondin related pathways relevant to the tumor microenvironment.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:8
Cell Line
IST-Mes2
Primary Disease
Pleural mesothelioma
Lineage
Pleura
Lineage Subtype
Pleural mesothelioma
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
DMEM & FBS & Glutamine
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
B3GLCT
Full Name
Beta 3-glucosyltransferase
Alternative Name
B3Glc-T, B3GTL, B3GALTL
Location
13q12.3
Gene ID
145173
Summary
Beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats; defects cause Peters-plus syndrome.
For Research Use Only.
Online Inquiry
Copyright © Creative Biolabs. All Rights Reserved.