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GlycoErase™ FUT4 Knockout Human Ovarian Cancer Cell A2780

CAT#: GLJF-0525-JF1045

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Overview Specification Target Information Related Products
Overview
Description
The FUT4 knockout A2780 cell line, lacking fucosyltransferase 4 crucial for CD15 antigen synthesis, enables the investigation of CD15 antigen's role in ovarian cancer, potentially impacting cell signaling, immune recognition, and CD15-related functions in tumor development and progression.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:3~1:6
Cell Line
A2780
Primary Disease
Ovarian Epithelial Tumor
Lineage
Ovary/Fallopian Tube
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Glutamine & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT4
Full Name
Fucosyltransferase 4
Alternative Name
FUC-TIV, FCT3A, CD15, ELFT
Location
11q21
Gene ID
2526
Summary
Catalyzes the synthesis of the non-sialylated antigen Lewis x (CD15) by transferring fucose to N-acetyllactosamine polysaccharides.
For Research Use Only.
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