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GlycoErase™ STBD1 Knockout Jurkat Cell Line

CAT#: GLJF-0825-JF832

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Overview
Description
GlycoErase™ STBD1 knockout Jurkat cell line is a Jurkat model in which STBD1 expression has been eliminated. STBD1 is a glycogen-binding protein that links glycogen particles to intracellular trafficking and glycophagy, localizing to T-tubules, endoplasmic reticulum, and perinuclear regions. This knockout enables studies of glycogen turnover via selective autophagy, organelle targeting of glycogen, and energy homeostasis, supporting applications in metabolic disease modeling and glyco-cell biology.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Suspension-growing
Passage Ratio
1:3~1:5
Cell Line
Jurkat cell line
Primary Disease
T-cell acute lymphoblastic leukemia (T-ALL)
Lineage
T Lymphocyte
Lineage Subtype
T-cell acute lymphoblastic leukemia (T-ALL)
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
STBD1
Full Name
Starch Binding Domain 1
Alternative Name
GENEX3414; GENX-3414
Location
4q21.1
Gene ID
Summary
Enables enzyme binding activity and glycogen binding activity. Involved in glycophagy and intracellular transport. Located in T-tubule; endoplasmic reticulum; and perinuclear region of cytoplasm.
For Research Use Only.
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