GlycoErase™ STBD1 Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF484)

Description	GlycoErase™ STBD1 knockout HEK293 cell line is a HEK293 model with STBD1 eliminated. STBD1 encodes a glycogen-binding protein that tethers glycogen to intracellular organelles and mediates glycophagy. The knockout in HEK293 enables study of glycogen turnover via selective autophagy, perinuclear/organelle targeting of glycogen, and its role in human energy regulation, supporting applications in metabolic research, glycogen-related pathologies, and glyco-cell biology.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	STBD1
Full Name	Starch Binding Domain 1
Alternative Name	GENEX3414; GENX-3414
Location	4q21.1
Gene ID	8987
Summary	The encoded protein binds enzymes and glycogen, participating in glycophagy and intracellular transport. It localizes to the T-tubule, endoplasmic reticulum, and perinuclear cytoplasm.