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GlycoErase™ STBD1 Knockout HEK293 Cell Line

CAT#: GLJF-0825-JF484

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Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ STBD1 knockout HEK293 cell line is a HEK293 model with STBD1 eliminated. STBD1 encodes a glycogen-binding protein that tethers glycogen to intracellular organelles and mediates glycophagy. The knockout in HEK293 enables study of glycogen turnover via selective autophagy, perinuclear/organelle targeting of glycogen, and its role in human energy regulation, supporting applications in metabolic research, glycogen-related pathologies, and glyco-cell biology.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial-like, adherent
Passage Ratio
1:2~1:4
Cell Line
HEK293
Lineage
Embryonic kidney
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
STBD1
Full Name
Starch Binding Domain 1
Alternative Name
GENEX3414; GENX-3414
Location
4q21.1
Gene ID
8987
Summary
The encoded protein binds enzymes and glycogen, participating in glycophagy and intracellular transport. It localizes to the T-tubule, endoplasmic reticulum, and perinuclear cytoplasm.
For Research Use Only.
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