GlycoFlux™ Human GSK3A Overexpression Glycoengineered Cell (CAT#: GLJF-0925-JF24)

Description	GlycoFlux™ human GSK3A overexpression glycoengineered cell is a stable cell line with increased GSK3α kinase activity impacting glycogen synthase and multiple signaling hubs. It enables signal-to-glycome mapping-quantifying how kinase tone alters Golgi trafficking, glycosyltransferase expression, and receptor N-glycan topology-plus drug mechanism studies that pair pathway readouts (WNT/PI3K) with glycoprotein maturation and endocytosis metrics.
Product Type	Overexpression Cell Lines
Cell Line	As requested by the client.

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	qPCR, Sanger Sequencing
Application	Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	GSK3A
Full Name	Glycogen Synthase Kinase 3 Alpha
Location	19q13.2
Gene ID	2931
Summary	This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.