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Recombinant Human CP protein (NP_000087.1) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.