Recombinant Human F5 Protein, Glycoengineered Mannose-5 Pichia pastoris

Recombinant Human F5 protein (NP_000121.2) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.

Glycoengineered Mannose-5 Pichia pastoris

Human

His-tag, FC-tag

>90%, determined by SDS-PAGE.

Regular batch

None

F5

Coagulation factor V

This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance.

Coagulation Factor V; Coagulation Factor V (Proaccelerin, Labile Factor); Activated Protein C Cofactor; Coagulation Factor V Jinjiang A2 Domain; Proaccelerin, Labile Factor; Factor V Leiden; RPRGL1; THPH2; PCCF; FVL