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Recombinant Human GDF3 protein (NP_065685.1) is produced in Glycoengineered Mannose-5 Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with a mannose-5 structure at N-linked sites.
The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development.