Recombinant Sudan ebolavirus Pre-small/secreted glycoprotein (GP) (33-372 aa), E. coli, Biotin conjugation (CAT#: GPX-332-EB-J)

Product Overview	Recombinant Sudan ebolavirus (strain Boniface-76) (SEBOV) Pre-small/secreted glycoprotein (33-372 aa) was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	E. coli
Species	Sudan ebolavirus (strain Boniface-76) (SEBOV)
Fragment	33-372 aa
Sequence	MPLGVVTN STLEVTEIDQ LVCKDHLAST DQLKSVGLNL EGSGVSTDIP SATKRWGFRS GVPPQVVSYE AGEWAENCYN LEIKKPDGSE CLPPPPDGVR GFPRCRYVHK AQGTGPCPGD YAFHKDGAFF LYDRLASTVI YRGVNFAEGV IAFLILAKPK ETFLQSPPIR EAANYTENTS SYYATSYLEY EIENFGAQHS TTLFKINNNT FVLLDRPHTP QFLFQLNDTI QLHQQLSNTT GKLIWTLDAN INADIGEWAF WENKKISPNN YVEKSCLSKL YRSTRQKTMM RHRRELQREE SPTGPPGSIR TWFQRIPLGW FHCTYQKGKQ HCRLRIRQKV EE
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Biotin

Target	GP
Full Name	Pre-small/secreted glycoprotein
Uniprot ID	P60172
Background	sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils.
Alternate Names	GP; Pre-small/secreted glycoprotein; pre-sGP; Small/secreted glycoprotein; sGP; Delta-peptide