GlycoErase™ AMY2A Knockout CHO-K1 Cell Line

GlycoErase™ AMY2A knockout CHO-K1 cell line is a Chinese hamster ovary (CHO-K1) model in which AMY2A expression has been eliminated. AMY2A encodes a pancreatic alpha-amylase isoenzyme that hydrolyzes 1,4-alpha-glucosidic bonds in dietary starch and glycogen, initiating carbohydrate digestion. The knockout of AMY2A in the CHO-K1 background enables studies on pancreatic enzyme function, carbohydrate breakdown, and digestive physiology, supporting applications in metabolic disease research, digestive enzyme biology, and therapeutic enzyme development.

KO Cell Lines

Hamster

Epithelial, adherent

1:3~1:5

CHO-K1

Chinese hamster ovary

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

FBS & Penicillin/Streptomycin & Proline & RPMI

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

AMY2A

Amylase Alpha 2A

PA; AMY2

This gene encodes a member of the alpha-amylase family of proteins. Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, catalyzing the first step in digestion of dietary starch and glycogen. This gene and several family members are present in a gene cluster on chromosome 1. This gene encodes an amylase isoenzyme produced by the pancreas.