GlycoErase™ HEK293T DPY19L2 Knockout Cell Line (CAT#: GLJF-0425-JF394)

Description	This DPY19L2-deficient HEK293T cell line provides a unique in vitro model for elucidating the precise role of C-mannosyltransferase 2 in spermatogenesis. Researchers can utilize this cell line to dissect the impact of DPY19L2 ablation on sperm head development and acrosome formation, key events in male fertility.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293T
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM & FBS & Penicillin/Streptomycin
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	DPY19L2
Full Name	Dpy-19 like C-mannosyltransferase 2
Alternative Name	SPATA34, FLJ32949
Location	12q14.2
Gene ID	283417
Summary	Required for sperm head elongation and acrosome formation during spermatogenesis, essential for male fertility.