GlycoErase™ SLC35D2 Knockout Human Thyroid Carcinoma Cell 8305C (CAT#: GLJF-0525-JF725)

Description	The SLC35D2 knockout 8305C cell line, deficient in solute carrier family 35 member D2, a nucleotide sugar transporter in the Golgi apparatus, enables the study of Golgi nucleotide sugar transport disruption in thyroid carcinoma, potentially broadly impacting Golgi glycosylation and nucleotide sugar availability for glycosylation pathways in thyroid cells.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Large spindle-shaped cell, adherent
Passage Ratio	1:3~1:6
Cell Line	8305C
Primary Disease	Anaplastic Thyroid Cancer
Lineage	Thyroid

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	SLC35D2
Full Name	Solute carrier family 35 member D2
Alternative Name	SQV7L, UGTrel8
Location	9q22.32
Gene ID	11046
Summary	Functions as a nucleotide sugar transporter, specifically transporting UDP-N-acetylglucosamine into the Golgi apparatus for use in glycosylation reactions.