PI(3,4,5)P3 18:0/20:4

Phosphatidylinositol 3,4,5-trisphosphate (PIP3) is a highly purified, synthetic lipid that serves as a fundamental second messenger. Generated by the enzyme PI 3-kinase, PIP3 initiates numerous downstream cascades that regulate key cellular processes, including cell division, growth, survival, membrane reorganization, and sugar uptake. Its activity is tightly regulated by the PTEN phosphatase, which removes the phosphate group.

799268-60-3

PI(3,4,5)P3 18:0/20:4; D-myo-phosphatidylinositol 3,4,5-trisphosphate 18:0/20:4

C₄₇H₈₂Na₄O₂₂P₄

1,214.99

InChI=1S/C47H86O22P4.4H3N/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(49)65-39(37-63-40(48)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2)38-64-73(61,62)69-44-42(50)45(66-70(52,53)54)47(68-72(58,59)60)46(43(44)51)67-71(55,56)57;;;;/h11,13,17,19,22,24,28,30,39,42-47,50-51H,3-10,12,14-16,18,20-21,23,25-27,29,31-38H2,1-2H3,(H,61,62)(H2,52,53,54)(H2,55,56,57)(H2,58,59,60);4*1H3/b13-11-,19-17-,24-22-,30-28-;;;;/t39-,42+,43+,44?,45-,46+,47?;;;;/m1..../s1

HIQNCTCJCORHBS-PRERETILSA-N

Min 95%

Dried by centrifugal evaporation from a solution.

Conforms to structure

Store at -20°C for long term storage.