Recombinant Human HP Protein, Glycoengineered Pichia pastoris

Recombinant Human HP protein (NP_001119574.1) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.

Glycoengineered Pichia pastoris

Human

His-Tag, FC-Tag or other Tags as required.

>90%

Regular batch

None

HP

Haptoglobin

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia.

BP; HPA1S; HP2ALPHA2