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Recombinant Rabies virus (strain Pasteur vaccins/PV) (RABV) Glycoprotein (20-524 aa), E. coli

CAT#: GP05-368J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Rabies virus (strain Pasteur vaccins/PV) (RABV) Glycoprotein (NP_056796.1) (20-524 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.
Biological Activity
Measured by its binding ability in a functional ELISA.
Source
E. coli cell-free expression system
Species
Rabies virus (strain Pasteur vaccins/PV) (RABV)
Fragment
20-524 aa
Tag
His-tag or Tag free
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
G
Full Name
Glycoprotein
Gene ID
1489856
Uniprot ID
P08667
Accession Number
NP_056796.1
Background
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names
Glycoprotein
For Research Use Only.
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