Recombinant Rabies virus (strain Pasteur vaccins/PV) (RABV) Glycoprotein (20-524 aa), E. coli (CAT#: GP05-368J)

Product Overview	Recombinant Rabies virus (strain Pasteur vaccins/PV) (RABV) Glycoprotein (NP_056796.1) (20-524 aa) was produced using E. coli cell-free expression system with a His-tag or Tag free. Measured by its binding ability in a functional ELISA.
Biological Activity	Measured by its binding ability in a functional ELISA.
Source	E. coli cell-free expression system
Species	Rabies virus (strain Pasteur vaccins/PV) (RABV)
Fragment	20-524 aa
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	G
Full Name	Glycoprotein
Gene ID	1489856
Uniprot ID	P08667
Accession Number	NP_056796.1
Background	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names	Glycoprotein