Recombinant Zaire ebolavirus (strain Mayinga-76) Pre-small/secreted glycoprotein (GP) (33-364 aa), E. coli (CAT#: GPX-331-E-J)

Product Overview	Recombinant Zaire ebolavirus (strain Mayinga-76) (ZEBOV) Pre-small/secreted glycoprotein (NP_066247.1) (33-364 aa) was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	E. coli
Species	Zaire ebolavirus (strain Mayinga-76) (ZEBOV)
Fragment	33-364 aa
Sequence	IPLGVIHN STLQVSDVDK LVCRDKLSST NQLRSVGLNL EGNGVATDVP SATKRWGFRS GVPPKVVNYE AGEWAENCYN LEIKKPDGSE CLPAAPDGIR GFPRCRYVHK VSGTGPCAGD FAFHKEGAFF LYDRLASTVI YRGTTFAEGV VAFLILPQAK KDFFSSHPLR EPVNATEDPS SGYYSTTIRY QATGFGTNET EYLFEVDNLT YVQLESRFTP QFLLQLNETI YTSGKRSNTT GKLIWKVNPE IDTTIGEWAF WETKKTSLEK FAVKSCLSQL YQTEPKTSVV RVRRELLPTQ GPTQQLKTTK SWLQKIPLQW FKCTVKEGKL QCRI
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	GP
Full Name	Pre-small/secreted glycoprotein
Gene ID	911829
Uniprot ID	P60170
Accession Number	NP_066247.1
Background	sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils.
Alternate Names	GP; Pre-small/secreted glycoprotein; pre-sGP; Small/secreted glycoprotein; sGP; Delta-peptide