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GlycoErase™ FUT3 Knockout CHO-K1 Cell Line

CAT#: GLJF-0425-JF20

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Overview Specification Target Information Related Products
Overview
Description
The FUT3 knockout CHO-K1 cell line explores FUT3, fucosyltransferase 3, in CHO-K1 cells. FUT3 synthesizes Lewis histo-blood group antigens on glycosphingolipids. FUT3 knockout in CHO cells may disrupt Lewis antigen synthesis, impacting glycosphingolipid fucosylation study relevant to CHO cell membrane engineering.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, adherent
Passage Ratio
1:3~1:5
Cell Line
CHO-K1
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
FUT3
Full Name
Fucosyltransferase 3
Alternative Name
CD174, LE
Summary
Generates fucosylated glycosphingolipids that play diverse roles in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion.
For Research Use Only.
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