GlycoErase™ HEK293T B3GNT2 Knockout Cell Line

We are pleased to introduce a B3GNT2 knockout HEK293T cell line, specifically designed to aid in the study of poly-N-acetyllactosamine chain biosynthesis. This cell line, deficient in the B3GNT2-encoded UDP-GlcNAc:betaGal beta-1,3-O-acetylglucosaminyltransferase 2, provides a unique opportunity to study the role of this enzyme in the synthesis of these complex glycan structures. Leveraging the versatility of HEK293T cells as a platform for gene function and regulation studies, researchers can utilize this model to gain deeper insights into the complexities of glycosylation.

KO Cell Lines

Human

Epithelial-like, adherent

1:2~1:4

HEK293T

Embryonic kidney

>90%

The sterility test indicated an absence of microbial growth.

STR identification

Negative

Negative for HIV, HBV and HCV.

We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.

PCR, Sanger Sequencing

DMEM & FBS & Penicillin/Streptomycin

Functional assay

1 M cells/vial*2

Frozen

Dry ice

Made to order

Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.

This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

B3GNT2

UDP-GlcNAc:BetaGal Beta-1,3-O-acetylglucosaminyltransferase 2

B3GNT1, BETA3GNT, B3GN-T1, B3GNT-2, B3GN-T2

2p15

Type II transmembrane protein that prefers lacto-N-neotetraose as a substrate and participates in the biosynthesis of poly-N-acetyllactosamine chains.