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GlycoErase™ B3GNT2 Knockout CHO-S Cell Line

CAT#: GLJF-0425-JF244

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Overview
Description
To analyze B3GNT2 UDP-GlcNAc:betaGal beta-1,3-O-acetylglucosaminyltransferase 2 function in CHO-S cells, and to elucidate its role in poly-N-acetyllactosamine chain biosynthesis, the B3GNT2 knockout CHO-S cell line is utilized to examine poly-N-acetyllactosamine chain biosynthesis disruption and its potential consequences for related glycan structures and cellular functions in CHO-S cells.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, suspension growth
Passage Ratio
1:3~1:5
Cell Line
CHO-S
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
CDMF & Glutamine & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
B3GNT2
Full Name
UDP-GlcNAc:BetaGal Beta-1,3-O-acetylglucosaminyltransferase 2
Alternative Name
B3GNT1, BETA3GNT, B3GN-T1, B3GNT-2, B3GN-T2
Location
2p15
Gene ID
Summary
Type II transmembrane protein that prefers lacto-N-neotetraose as a substrate and participates in the biosynthesis of poly-N-acetyllactosamine chains.
For Research Use Only.
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