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GlycoErase™ ST3GAL4 Knockout CHO-S Cell Line

CAT#: GLJF-0425-JF217

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Overview Specification Target Information Related Products
Overview
Description
To probe ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 function in CHO-S cells, and to determine its role in Golgi membrane-localized alpha-2,3-sialylation, the ST3GAL4 knockout CHO-S cell line is established as a research tool to investigate alpha-2,3-sialylation disruption and its potential effects on sialylation patterns and glycoprotein sialylation in CHO-S cells.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, suspension growth
Passage Ratio
1:3~1:5
Cell Line
CHO-S
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
CDMF & Glutamine & Penicillin/Streptomycin
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
ST3GAL4
Full Name
ST3 Beta-galactoside alpha-2,3-sialyltransferase 4
Alternative Name
SIAT4, STZ, NANTA3, SIAT4C, SAT3, CGS23, FLJ11867
Location
11q24.2
Gene ID
6484
Summary
Golgi-localized glycosyltransferase involved in protein glycosylation; may be secreted and potentially contributes to the regulation of sialyl Lewis X antigen expression during inflammation.
For Research Use Only.
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