Recombinant Human C-type lectin domain containing 7a (CLEC7A) protein, NS0 cell line

Recombinant Human C-type lectin domain containing 7a (CLEC7A) protein (NP_072092) was expressed in NS0 cell line. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.

Determined by its binding ability in a functional ELISA.

NS0 cell line

Human

>90%, determined by SDS-PAGE and HPLC

Unconjugated

CLEC7A

C-type lectin domain containing 7a

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

BGR; CD369; CANDF4; SCARE2; DECTIN1; CLECSF12; CLEC7A; C-type lectin domain containing 7a