Recombinant Rabies virus (strain ERA) (RABV) Glycoprotein (G), Mammalian cell (CAT#: GPX-025-M-J)

Product Overview	Recombinant Rabies virus (strain ERA) (RABV) Glycoprotein was expressed in Mammalian cell with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	Mammalian cell
Species	Rabies virus (strain ERA) (RABV)
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Unconjugated

Target	G
Full Name	Glycoprotein
Uniprot ID	P03524
Background	Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Alternate Names	G; Glycoprotein