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GlycoErase™ B3GNT2 Knockout Human Skin Cancer Cell A2058

CAT#: GLJF-0525-JF1012

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Overview Specification Target Information Related Products
Overview
Description
The B3GNT2 knockout A2058 cell line, lacking beta-1,3-N-acetylglucosaminyltransferase 2 involved in poly-N-acetyllactosamine chain biosynthesis, allows for the study of the disruption of poly-N-acetyllactosamine chains in melanoma, potentially affecting cell surface carbohydrate structures and interactions.
Product Type
KO Cell Lines
Species
Human
Cell Morphology
Epithelial cells, adherent
Passage Ratio
1:2~1:3
Cell Line
A2058
Primary Disease
Melanoma
Lineage
Skin
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
EMEM & FBS & Glutamine
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
B3GNT2
Full Name
UDP-GlcNAc:BetaGal Beta-1,3-O-acetylglucosaminyltransferase 2
Alternative Name
B3GNT1, BETA3GNT, B3GN-T1, B3GNT-2, B3GN-T2
Location
2p15
Gene ID
10678
Summary
Type II transmembrane protein that prefers lacto-N-neotetraose as a substrate and participates in the biosynthesis of poly-N-acetyllactosamine chains.
For Research Use Only.
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