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Inositol phosphates are essential second messenger molecules involved in a broad spectrum of cellular functions, including energy metabolism and signaling. Inositol 1,2,6-trisphosphate (Ins(1,2,6)P3), an analog of Ins(1,4,5)P3, has demonstrated clinically relevant activities, such as inhibiting inflammatory processes, preventing paw edema in skin burn models, blocking vasoconstriction induced by neuropeptide Y, and improving acute nerve function disorders observed in diabetic conditions.