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Recombinant Human CLU protein (NP_001822.3) is produced in Fuco-Adjusted Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with different fucosylation degree.
The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.