Recombinant Human GDF1 Protein, Glycoengineered Pichia pastoris

Recombinant Human GDF1 protein (NP_001483.3) is produced in Glycoengineered Pichia pastoris. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.

Glycoengineered Pichia pastoris

Human

His-Tag, FC-Tag or other Tags as required.

>90%

Regular batch

None

GDF1

Embryonic growth/differentiation factor 1

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1.

RAI; DORV; LAG1; UOG1; CERS1; CHTD6; DTGA3; LASS1