Recombinant Rinderpest virus (RDV) (strain L) Hemagglutinin glycoprotein (H) (1-609 aa), E. coli

Recombinant Rinderpest virus (RDV) (strain L) Hemagglutinin glycoprotein (1-609 aa) was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.

Determined by its binding ability in a functional ELISA.

Rinderpest virus (RDV) (strain L)

1-609 aa

MSSPRDRVNAFYKDNLQFKNTRVVLNKEQLLIERPYMLLAVLFVMFLSLVGLLAIAGIRL HRAAVNTAEINSGLTTSIDITKSIEYQVKDVLTPLFKIIGDEVGLRTPQRFTDLTKFISD KIKFLNPDKEYDFRDINWCISPPERIKINYDQYCAHTAAEELITMLVNSSLAGTSVLPTS LVNLGRSCTGSTTTKGQFSNMSLALSGIYSGRGYNISSMITITEKGMYGSTYLVGKHNQG ARRPSTAWQRDYRVFEVGIIRELGLGTPVFHMTNYLELPRQPELEICMLALGEFKLAALC LADNSVALHYGGLRDDHKIRFVKLGVWPSPADSDTLATLSAVDPTLDGLYITTHRGIIAA GKAVWVVPVTRTDDQRKMGQCRREACREKPPPFCNSTDWEPLEAGRIPAYGILTIRLGLA DKLKLTIISEFGPLITHDSGMDLYTPLDGNEYWLTIPPLQNSALGTVNTLVLEPSLKISP NILTLPIRSGGGDCYTPTYLSDLADDDVKLSSNLVILPSRNLQYVSATYDTSRVEHAIVY YIYSAGRLSSYYYPVKLPIKGDPVSLQIGCFPWGLKLWCHHFCSVIDSGTRKQVTHTGAV GIEITCNSR

His-tag or Tag free

>90%, determined by SDS-PAGE.

Unconjugated

H

Hemagglutinin glycoprotein

Attaches the virus to cell receptors and thereby initiating infection. Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion. Down-regulates human MCP/CD46 cell surface expression.

Hemagglutinin glycoprotein