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Recombinant Human CD47 molecule (NP_942088.1) (19-139 aa) was expressed in Mammalian cell with a 6xHis-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. The ED50 is 150 μg/mL. This product can be used in ELISA, WB, IP.
Biological Activity
Determined by its binding ability to human SIRPA in a functional ELISA. The ED50 is 150 μg/mL.
This protein has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus.