Close
0
Inquiry Basket

There is no product in the shopping cart, buy it!

Hot Products
Monosaccharide Products
Oligosaccharide Products
Polysaccharide Products
Carbohydrate-based Surfactant Products
Blood Group Antigen Products
Glycoprotein Products
Glycopeptide Products
Nucleotide Sugar Products
Glycoprotein Assay Kits
Comprehensive Glycoprotein Reagents
Glycoengineered Cell Products
Glycoengineering Viral Particle Products
Glycolipid Products

GlycoErase™ SIGLEC15 Knockout CHO-K1 Cell Line

CAT#: GLJF-0825-JF869

Datasheet Request COA
Overview Specification Target Information Related Products
Overview
Description
GlycoErase™ SIGLEC15 knockout CHO-K1 cell line is a CHO-K1 model lacking SIGLEC15 expression. SIGLEC15 regulates actin cytoskeleton organization, bone resorption, and osteoclast development, and is associated with plasma membrane complexes. Removal of SIGLEC15 in CHO-K1 provides a system to explore osteoclast biology, skeletal disease mechanisms, and cytoskeletal regulation, with applications in bone metabolism, therapeutic validation, and immune modulation.
Product Type
KO Cell Lines
Species
Hamster
Cell Morphology
Epithelial, adherent
Passage Ratio
1:3~1:5
Cell Line
CHO-K1
Lineage
Chinese hamster ovary
Specification
Cell Viability
>90%
Sterility Test
The sterility test indicated an absence of microbial growth.
Identity Test
STR identification
Mycoplasma Test
Negative
Virus Test
Negative for HIV, HBV and HCV.
Genetic Stability Testing
We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation
PCR, Sanger Sequencing
Culture Medium
FBS & Penicillin/Streptomycin & Proline & RPMI
Application
Functional assay
Size
1 M cells/vial*2
Product Format
Frozen
Shipping
Dry ice
Availability Status
Made to order
Handling Notes
Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer
This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target Information
Target
SIGLEC15
Full Name
Sialic Acid Binding Ig Like Lectin 15
Alternative Name
CD33L3, HsT1361, SIGLEC-15, Sialic Acid Binding Ig Like Lectin
Summary
This protein is predicted to regulate actin cytoskeleton organization, bone resorption, and osteoclast development. It is expected to be located in the membrane and to be part of a protein-containing complex, functioning actively in the plasma membrane.
For Research Use Only.
Online Inquiry
Copyright © Creative Biolabs. All Rights Reserved.